Picato Sap diluted too much to be effective, however I have used both Picato and the actual sap from the Euphorbia Peplus plant and I have gotten excellent Every day for 3 days and there is a strong reaction if the patient has surface basal cell cancer or any AK
I believe the label for this gel states that it is NOT a Generol mebutate in 5% concentration, but no more than 2%. Euphorbia Peplus (the sap) accounts for 5%. The labeling for this product states to use it every day for WEEKS, as opposed to what Picato advises. In addition, whereas Picato gels require refrigeration, this gel can be kept It has been five days since I have been using the gel, and I would say that there is a slight reaction, but nowhere near as severe It has now been 2 weeks since using AKs and no reactions have been reported in any of the two sites. There is just no benefit to this product, so I have to give it a one star rating.